Product Description
N-Nitrosodiethylamine (NDEA) is an organic compound with the formula Et2NNO (Et = C2H5). A member of the nitrosamines, it is a light-sensitive, volatile, clear yellow oil that is soluble in water, lipids, and other organic solvents. It has an amine or aromatic odor. It is used as gasoline and lubricant additive, antioxidant, and stabilizer for industry materials. When heated to decomposition, N-nitrosodiethylamine emits toxic fumes of nitrogen oxides. N-Nitrosodiethylamine affects DNA integrity, probably by alkylation, and is used in experimental research to induce liver tumorigenesis.[2] It is carcinogenic and mutagenic.[3] NDEA has also been found to perturb amino acid biosynthesis including arginine, as well as DNA damage repair and mitochondrial genome maintenance in yeast.Accurate Reference Material for ResearchN-Nitrosodiethylamine is tailored for use as a precise reference standard in laboratory settings, particularly in studies that explore biochemical and toxicological properties. Its high purity and stability make it a trusted compound in experimental protocols, ensuring reliable and reproducible results during scientific analysis.
Safe Storage and Handling PracticesThis chemical demands strict handling practices due to its toxicity and carcinogenic nature. Storage should be in a cool, dry, and well-ventilated area, far from oxidizing agents and heat sources. NDEA is shipped in secure glass bottles and must be managed in compliance with local and international hazardous substance guidelines.
FAQ's of N-Nitrosodiethylamine (NDEA):
Q: How should N-Nitrosodiethylamine (NDEA) be safely handled and stored in the laboratory?
A: NDEA must be handled in a fume hood, with appropriate personal protective equipment including gloves and eyewear, due to its toxicity and carcinogenic potential. Store the chemical in a tightly sealed glass bottle, in a cool, dry, and well-ventilated area, away from ignition sources and oxidizing agents.
Q: What are the primary research applications of N-Nitrosodiethylamine?
A: NDEA is primarily utilized as a reference material in biochemical research and toxicological studies. It serves as a control compound in experiments assessing nitrosamine-induced toxicology and is valuable for validating analytical methods involving carcinogenic compounds.
Q: When is it appropriate to use NDEA in an experimental context?
A: NDEA is used when precise calibration of analytical instruments or toxicological models is needed, such as in research examining carcinogenic mechanisms or assessing the efficacy of detection methods for nitrosamines in environmental or biological samples.
Q: Where can NDEA be procured, and in what packaging sizes?
A: NDEA is available through distributors, importers, manufacturers, suppliers, and traders, especially in India. It is offered in custom packaging sizes, typically in secure glass bottles, to meet varied laboratory requirements.
Q: What is the process for transporting NDEA, and what regulations must be observed?
A: Transport of NDEA must adhere to local and international hazardous chemical regulations, as specified by its UN Number 1650. Proper labeling, packaging, and documentation are mandatory, with shipping in well-protected glass bottles to minimize risks during transit.
Q: What are the key benefits of using NDEA in laboratory research?
A: Key benefits include its high purity, stable performance under recommended storage, and its established role as a reference compound for accurate analysis in both biochemical and toxicological research, contributing to trustworthy and reproducible scientific data.