Product Description
N-Nitrosodi-n-butylamine is a yellow, viscous, oily nitrosamine that is highly unstable in the presence of light. N-Nitrosodiethanolamine is ubiquitously found in the environment and is a contaminant formed by the reaction of nitrites with ethanolamines in a wide range of products including tobacco, pesticides, antifreeze and personal care products. This substance is only used for research purposes to induce tumors in experimental animals. N-Nitrosodiethanolamine is reasonably anticipated to be a human carcinogen.Precision in Pharmaceutical AnalysisN-Nitroso dibutylamine serves as a benchmark impurity in pharmaceutical quality control and research laboratories. Its consistent purity and analytical grade standard allow for reliable monitoring of product safety, ensuring compliance with regulatory requirements and industry best practices. Laboratories benefit from using NDBA to enhance the accuracy of impurity profiling.
Safe Handling and StorageGiven its carcinogenic potential, NDBA must be handled using appropriate protective measures, including gloves and eye protection. The compound remains stable when stored in cool, dry, well-ventilated spaces, away from ignition sources. Proper storage safeguards both users and the compound's integrity, preserving its effectiveness over its two-year shelf life.
FAQ's of N-Nitroso dibutylamine (NDBA) IMP:
Q: How should N-Nitroso dibutylamine be stored to maintain its stability and shelf life?
A: N-Nitroso dibutylamine should be stored in a cool, dry, and well-ventilated area, away from sources of ignition. Proper storage helps ensure stability and preserves its shelf life, which is up to two years under recommended conditions.
Q: What precautions are necessary when handling N-Nitroso dibutylamine in the laboratory?
A: Due to its carcinogenic hazard, users must handle NDBA with protective equipment such as gloves, lab coats, and safety goggles. Working in a well-ventilated environment and avoiding direct contact with the chemical are essential safety measures.
Q: When is N-Nitroso dibutylamine typically used in pharmaceutical applications?
A: NDBA is used as an impurity standard for monitoring and assessing pharmaceutical products, aiding in the quality control process during research and manufacturing to meet regulatory pharmacopoeial demands.
Q: Where can N-Nitroso dibutylamine be sourced, and what packaging options are available?
A: NDBA is available from distributors, importers, manufacturers, suppliers, and traders. It is supplied in secure glass bottles or drums, with packaging sizes customized to lab requirements across India.
Q: What is the benefit of using N-Nitroso dibutylamine in research laboratories?
A: Utilizing NDBA as a reference impurity enhances the precision and reliability of pharmaceutical impurity profiling, providing confidence in product safety and regulatory compliance for laboratories.
Q: How is N-Nitroso dibutylamine disposed of after use?
A: Waste containing NDBA should be handled as hazardous material and disposed of according to local regulations for laboratory chemicals, with reference to institutional safety protocols.